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Stochasticity and traffic jams in the transcription of ribosomal RNA: Intriguing role of termination and antitermination

In fast-growing bacteria, ribosomal RNA (rRNA) is required to be transcribed at very high rates to sustain the high cellular demand on ribosome synthesis. This results in dense traffic of RNA polymerases (RNAP). We developed a stochastic model, integrating results of single-molecule and quantitative...

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Detalhes bibliográficos
Main Authors: Klumpp, Stefan, Hwa, Terence
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2008
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2587539/
https://ncbi.nlm.nih.gov/pubmed/19017803
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0806084105
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