A proteolytic enzyme secreted by Proteus mirabilis degrades immunoglobulins of the immunoglobulin A1 (IgA1), IgA2, and IgG isotypes.

Proteus mirabilis strains associated with human urinary tract infections have previously been shown to secrete an extracellular metalloproteinase which cleaves serum immunoglobulin A (IgA). The enzyme has now been purified to apparent homogeneity from culture supernatants of P. mirabilis 64676. The...

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Publié dans:	Infect Immun
Auteurs principaux:	Loomes, L M, Senior, B W, Kerr, M A
Format:	Artigo
Langue:	Inglês
Publié:	American Society for Microbiology (ASM) 1990
Sujets:	Research Article
Accès en ligne:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC258753/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/2111288/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/iai.58.6.1979-1985.1990
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