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Inhibition of calcium/calmodulin kinase II alpha subunit expression results in epileptiform activity in cultured hippocampal neurons

Several models that develop epileptiform discharges and epilepsy have been associated with a decrease in the activity of calmodulin-dependent kinase II. However, none of these studies has demonstrated a causal relationship between a decrease in calcium/calmodulin kinase II activity and the developme...

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Detalhes bibliográficos
Main Authors: Churn, Severn B., Sombati, Sompong, Jakoi, Emma R., Sievert, Lawrence, DeLorenzo, Robert J.
Formato: Artigo
Idioma:Inglês
Publicado em: The National Academy of Sciences 2000
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC25875/
https://ncbi.nlm.nih.gov/pubmed/10779547
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