Lipopolysaccharide (LPS) Stimulation of Trophoblasts Induces Corticotrophin Releasing Hormone (CRH) Expression through MyD88

OBJECTIVE: We hypothesized that intrauterine infection may lead to placental CRH expression via Toll like receptor signaling. METHODS: In order to test this hypothesis JEG3 cells were stimulated with LPS, chlamydial heat shock protein 60 and IL1. CRH expression was assessed by RT-PCR. The signaling...

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Detalhes bibliográficos
Main Authors: Uh, Andy, Nicholson, Richard C., Gonzalez, Gustavo V., Simmons, Charles F., Gombart, Adrian, Smith, Roger, Equils, Ozlem
Formato: Artigo
Idioma:Inglês
Publicado em: 2008
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2587489/
https://ncbi.nlm.nih.gov/pubmed/18771998
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ajog.2008.06.091
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