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Studies in Chlorin Chemistry. III. A Practical Synthesis of C,D-Ring Symmetric Chlorins of Potential Utility in Photodynamic Therapy

[Image: see text] C,D-Ring symmetric chlorins 8 were prepared in 47-85% yield, on scales up to several hundred milligrams, by condensation of appropriately substituted bis-formyldihydro-dipyrrins 6 and dihydropyrromethane bis-carboxylic acids 7 in 5% TFA/CH(2)Cl(2) (25 examples). Target chlorins wer...

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Detalhes bibliográficos
Main Authors: O’Neal, William G., Roberts, William P., Ghosh, Indranath, Wang, Hui, Jacobi, Peter A.
Formato: Artigo
Idioma:Inglês
Publicado em: 2006
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2587451/
https://ncbi.nlm.nih.gov/pubmed/16626128
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/jo060041z
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