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Angiostatic activity of obtustatin as α1β1 integrin inhibitor in experimental melanoma growth
The presented results show the effect of targeting of collagen receptor, α1β1 integrin expressed on the endothelial cells on the development of experimental melanoma and pathological angiogenesis. Obtustatin, a snake venom KTS-disintegrin, was applied as a specific inhibitor of this integrin. This l...
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| Main Authors: | , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado: |
2008
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| Assuntos: | |
| Acceso en liña: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2587450/ https://ncbi.nlm.nih.gov/pubmed/18712720 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/ijc.23777 |
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