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Deficits in memory and motor performance in synaptotagmin IV mutant mice

Synaptotagmin (Syt) IV is a synaptic vesicle protein. Syt IV expression is induced in the rat hippocampus after systemic kainic acid treatment. To examine the functional role of this protein in vivo, we derived Syt IV null [Syt IV(−/−)] mutant mice. Studies with the rotorod revealed that the Syt IV...

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Udgivet i:Proc Natl Acad Sci U S A
Principais autores: Ferguson, Gregory D., Anagnostaras, Stephan G., Silva, Alcino J., Herschman, Harvey R.
Format: Artigo
Sprog:Inglês
Udgivet: National Academy of Sciences 2000
Fag:
Biological Sciences
Online adgang:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC25874/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/10792055/
https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.100104597
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