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Essential role of IFNβ and CD38 in TNFα-induced airway smooth muscle hyper-responsiveness

We recently identified autocrine interferon (IFN)β as a novel mechanism mediating tumor necrosis factor (TNF)α-induced expression of inflammatory genes in airway smooth muscle (ASM) cells, including CD38, known to regulate calcium signaling. Here, we investigated the putative involvement of IFNβ in...

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Bibliografiske detaljer
Main Authors: Jain, Deepika, Keslacy, Stefan, Tliba, Omar, Cao, Yang, Kierstein, Sonja, Amin, Kunjalata, Panettieri, Reynold A., Haczku, Angela, Amrani, Yassine
Format: Artigo
Sprog:Inglês
Udgivet: 2008
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2587232/
https://ncbi.nlm.nih.gov/pubmed/18514752
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.imbio.2007.12.002
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