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CALCIUM STORE-DEPENDENT AND INDEPENDENT REVERSAL OF STIM1 LOCALIZATION AND FUNCTION

Stim1 responds to depletion of ER Ca(2+) stores by rearranging from tubular structures throughout the ER into punctate structures near the plasma membrane, where it activates Orai store-operated Ca(2+) entry (SOCE) channels. However, the mechanism and structural determinants of the localization and...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Smyth, Jeremy T., DeHaven, Wayne I., Bird, Gary S., Putney, James W.
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2008
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2587154/
https://ncbi.nlm.nih.gov/pubmed/18285445
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1242/jcs.023903
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