Regulation of Motor Neuron Specification by GSK3-Mediated Phosphorylation of Neurogenin 2

The mechanisms by which proneural basic helix-loop-helix (bHLH) factors control neurogenesis have been characterized, but it is not known how they specify neuronal cell-type identity. Here we provide evidence that two conserved serine residues on the bHLH factor neurogenin 2 (Ngn2), S231 and S234, a...

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Main Authors: Ma, Yong-Chao, Song, Mi-Ryoung, Park, Jin P., Ho, Hsin-Yi Henry, Hu, Linda, Kurtev, Martin V., Zieg, Janine, Ma, Qiufu, Pfaff, Samuel L., Greenberg, Michael E.
Format: Artigo
Sprog:Inglês
Udgivet: 2008
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Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2587148/
https://ncbi.nlm.nih.gov/pubmed/18400164
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.neuron.2008.01.037
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