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5-tert-Butyl-2-(4′-[(18)F]fluoropropynylphenyl)-1,3-dithiane Oxides: Potential New GABA(A) Receptor Radioligands

As potential new ligands targeting the GABA receptor ionophore binding site, trans-5-tert-butyl-2-(4′-fluoropropynylphenyl)-2-methyl-1,1-dioxo-1,3-dithiane 1 and cis- and trans-5-tert-butyl-2-(4′-fluoropropynylphenyl)-2-methyl-1,1,3,3-tetroxo-1,3-dithiane 2 were selected for radiolabeling and initia...

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Detalhes bibliográficos
Main Authors: Li, Xuehe, Jung, Yong-Woon, Snyder, Scott E., Blair, Joseph, Sherman, Philip S., Desmond, Timothy, Frey, Kirk A., Kilbourn, Michael R.
Formato: Artigo
Idioma:Inglês
Publicado em: 2007
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2587131/
https://ncbi.nlm.nih.gov/pubmed/18589299
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.nucmedbio.2007.08.003
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