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Increased Apoptosis in High-Fat Diet–Induced Nonalcoholic Steatohepatitis in Rats Is Associated with c-Jun NH(2)-Terminal Kinase Activation and Elevated Proapoptotic Bax

Hepatocyte apoptosis in addition to oxidative stress could be a key component in the pathogenesis of nonalcoholic steatohepatitis (NASH). However, the underlying mechanisms of hepatocellular apoptotic response associated with oxidative stress have not been investigated in high-fat diet (HFD)–induced...

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Hlavní autoři: Wang, Yan, Ausman, Lynne M., Russell, Robert M., Greenberg, Andrew S., Wang, Xiang-Dong
Médium: Artigo
Jazyk:Inglês
Vydáno: 2008
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC2587062/
https://ncbi.nlm.nih.gov/pubmed/18806094
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