The multifunctional protein glyceraldehyde-3-phosphate dehydrogenase is both regulated and controls CSF-1 mRNA stability in ovarian cancer

Although GAPDH’s predilection for AU-rich elements has long been known, the expected connection between GAPDH and control of mRNA stability has never been made. Recently, we described GAPDH binding the AU-rich terminal 144nt of the CSF-1 3′UTR, which we showed is an mRNA decay element in ovarian can...

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Main Authors: Zhou, Yi, Yi, Xiaofang, Stoffer, Jha’Nae B., Bonafe, Nathalie, Gilmore-Hebert, Maureen, McAlpine, Jessica, Chambers, Setsuko K.
Formato: Artigo
Idioma:Inglês
Publicado: 2008
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Article
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC2587019/
https://ncbi.nlm.nih.gov/pubmed/18708368
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/1541-7786.MCR-07-2170
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