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Structural Basis for Nuclear Receptor Corepressor (NCoR) Recruitment by Antagonist Liganded Androgen Receptor
Androgen receptor (AR) recruitment of transcriptional corepressors NCoR and SMRT can be enhanced by antagonists such as mifepristone. This study shows that enhanced NCoR binding to the mifepristone liganded AR is mediated by the NCoR C-terminal N1 CoRNR box, and that this selectivity is due to charg...
Tallennettuna:
| Päätekijät: | , , , |
|---|---|
| Aineistotyyppi: | Artigo |
| Kieli: | Inglês |
| Julkaistu: |
2008
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| Aiheet: | |
| Linkit: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2587007/ https://ncbi.nlm.nih.gov/pubmed/18852122 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/1535-7163.MCT-08-0461 |
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