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Reciprocal function of Gαi2 and Gαi3 in graft-versus-host disease

This study delineates specific functions of Gαi2 and Gαi3 in T cell mobilization during the development of graft-versus-host disease (GVHD) and reveals reciprocal effects of these two G proteins on the onset and morbidity of the disease. A deletion of Gαi2 hampered trafficking of pathogenic T cells...

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Detalhes bibliográficos
Main Authors: Jin, Yong Zhu, Thompson, Brian D., Zhou, Zho Yan, Fu, Yineng, Birnbaumer, Lutz, Wu, Mei X.
Formato: Artigo
Idioma:Inglês
Publicado em: 2008
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2586968/
https://ncbi.nlm.nih.gov/pubmed/18521956
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/eji.200737738
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