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Ventral specification and perturbed boundary formation in the mouse midbrain in the absence of Hedgehog signaling

Although Hedgehog (HH) signaling plays a critical role in patterning the ventral midbrain, its role in early midbrain specification is not known. We examined the midbrains of sonic hedgehog (Shh) and smoothened (Smo) mutant mice where HH signaling is respectively attenuated and eliminated. We show t...

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Detaylı Bibliyografya
Asıl Yazarlar: Fogel, Jennifer L., Chiang, Chin, Huang, Xi, Agarwala, Seema
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: 2008
Konular:
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC2586936/
https://ncbi.nlm.nih.gov/pubmed/18429041
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/dvdy.21536
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