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Widespread receptivity to neuropeptide PDF throughout the neuronal circadian clock network of Drosophila revealed by real-time cyclic AMP imaging

The neuropeptide PDF is released by sixteen clock neurons in Drosophila and helps maintain circadian activity rhythms by coordinating a network of ~150 neuronal clocks. Whether PDF acts directly on elements of this neural network remains unknown. We address this question by adapting Epac1-camps, a g...

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Detalhes bibliográficos
Main Authors: Shafer, Orie T., Kim, Dong Jo, Dunbar-Yaffe, Richard, Nikolaev, Viacheslav O., Lohse, Martin J., Taghert, Paul H.
Formato: Artigo
Idioma:Inglês
Publicado em: 2008
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2586874/
https://ncbi.nlm.nih.gov/pubmed/18439407
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.neuron.2008.02.018
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