Signal transduction in human platelets and inflammatory mediator release induced by genetically cloned hemolysin-positive and -negative Escherichia coli strains.

Incubation of human platelets with the hemolysin-producing Escherichia coli strain K-12 (pANN5211) induced the activation of protein kinase C, aggregation of platelets, calcium influx, low amounts of 12-hydroxyeicosatetraenoic acid (12-HETE), and release of serotonin from dense granules. Nonhemolyti...

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Detalhes bibliográficos
Publicado no:Infect Immun
Main Authors: König, B, Schönfeld, W, Scheffer, J, König, W
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology (ASM) 1990
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC258683/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/1971256/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/iai.58.6.1591-1599.1990
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