Phorbol esters enhance the cyclic GMP response of T84 cells to the heat-stable enterotoxin of Escherichia coli (STa).

We examined the effect of protein kinase C (PKC) activation on the cyclic GMP response to heat-stable enterotoxin (STa) in a colonic carcinoma intestinal epithelial cell line, T84 cells. Our results demonstrate that the active phorbol ester analog, phorbol dibutyrate, but not the inactive alpha-phor...

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Detalles Bibliográficos
Publicado en:Infect Immun
Autores principales: Weikel, C S, Spann, C L, Chambers, C P, Crane, J K, Linden, J, Hewlett, E L
Formato: Artigo
Lenguaje:Inglês
Publicado: American Society for Microbiology (ASM) 1990
Materias:
Research Article
Acceso en línea:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC258639/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/1969850/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/iai.58.5.1402-1407.1990
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