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Phorbol esters enhance the cyclic GMP response of T84 cells to the heat-stable enterotoxin of Escherichia coli (STa).

We examined the effect of protein kinase C (PKC) activation on the cyclic GMP response to heat-stable enterotoxin (STa) in a colonic carcinoma intestinal epithelial cell line, T84 cells. Our results demonstrate that the active phorbol ester analog, phorbol dibutyrate, but not the inactive alpha-phor...

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Détails bibliographiques
Auteurs principaux: Weikel, C S, Spann, C L, Chambers, C P, Crane, J K, Linden, J, Hewlett, E L
Format: Artigo
Langue:Inglês
Publié: 1990
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC258639/
https://ncbi.nlm.nih.gov/pubmed/1969850
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