Specific labeling of cysteine proteinases in pathogenic and nonpathogenic Entamoeba histolytica.

Growth of Entamoeba histolytica trophozoites was inhibited by 50% at low concentrations (2.0 micrograms/ml) of the diazopeptidyl inhibitor benzyloxycarbonyl-leucyl-L-tyrosyldiazomethane (Z-L-Leu-L-Tyr-CHN2). Iodination of the tyrosine residue lowered the growth inhibitory efficacy of the diazopeptid...

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Detalhes bibliográficos
Publicado no:Infect Immun
Main Authors: de Meester, F, Shaw, E, Scholze, H, Stolarsky, T, Mirelman, D
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology (ASM) 1990
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC258638/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/2323821/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/iai.58.5.1396-1401.1990
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