NADPH Oxidase-dependent Generation of Lysophosphatidylserine Enhances Clearance of Activated and Dying Neutrophils via G2A

Exofacial phosphatidylserine (PS) is an important ligand mediating apoptotic cell clearance by phagocytes. Oxidation of PS fatty acyl groups (oxPS) during apoptosis reportedly mediates recognition through scavenger receptors. Given the oxidative capacity of the neutrophil NADPH oxidase, we sought to...

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Библиографические подробности
Главные авторы: Frasch, S. Courtney, Berry, Karin Zemski, Fernandez-Boyanapalli, Ruby, Jin, Hyun-Sun, Leslie, Christina, Henson, Peter M., Murphy, Robert C., Bratton, Donna L.
Формат: Artigo
Язык:Inglês
Опубликовано: American Society for Biochemistry and Molecular Biology 2008
Предметы:
Lipids and Lipoproteins: Metabolism, Regulation, and Signaling
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC2586279/
https://ncbi.nlm.nih.gov/pubmed/18824544
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M807047200
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