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Human Mutation in the Anti-apoptotic Heat Shock Protein 20 Abrogates Its Cardioprotective Effects
The small heat shock protein Hsp20 protects cardiomyocytes against apoptosis, and phosphorylation at its Ser(16) site enhances its cardioprotection. To determine whether genetic variants exist in human Hsp20, which may modify these beneficial effects, we sequenced the coding region of the Hsp20 gene...
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| Hauptverfasser: | , , , , , , |
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| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
American Society for Biochemistry and Molecular Biology
2008
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2586274/ https://ncbi.nlm.nih.gov/pubmed/18790732 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M802307200 |
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