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APOBEC3G Subunits Self-associate via the C-terminal Deaminase Domain

Human APOBEC3G (hA3G) is a cytidine deaminase active on HIV single-stranded DNA. Small angle x-ray scattering and molecular envelope restorations predicted a C-terminal dimeric model for RNA-depleted hA3G in solution. Each subunit was elongated, suggesting that individual domains of hA3G are solvent...

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Bibliographische Detailangaben
Hauptverfasser: Bennett, Ryan P., Salter, Jason D., Liu, Xiang, Wedekind, Joseph E., Smith, Harold C.
Format: Artigo
Sprache:Inglês
Veröffentlicht: American Society for Biochemistry and Molecular Biology 2008
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2586250/
https://ncbi.nlm.nih.gov/pubmed/18842592
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M803726200
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