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APOBEC3G Subunits Self-associate via the C-terminal Deaminase Domain
Human APOBEC3G (hA3G) is a cytidine deaminase active on HIV single-stranded DNA. Small angle x-ray scattering and molecular envelope restorations predicted a C-terminal dimeric model for RNA-depleted hA3G in solution. Each subunit was elongated, suggesting that individual domains of hA3G are solvent...
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| Main Authors: | , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
American Society for Biochemistry and Molecular Biology
2008
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2586250/ https://ncbi.nlm.nih.gov/pubmed/18842592 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M803726200 |
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