Both Leukotoxin and Poly-N-Acetylglucosamine Surface Polysaccharide Protect Aggregatibacter actinomycetemcomitans Cells from Macrophage Killing

Two virulence factors produced by the periodontopathogen Aggregatibacter actinomycetemcomitans are leukotoxin, a secreted lipoprotein that kills human polymorphonuclear leukocytes and macrophages, and poly-N-acetylglucosamine (PGA), a surface polysaccharide that mediates intercellular adhesion, biof...

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Bibliographic Details
Main Authors: Venketaraman, Vishwanath, Lin, Albert K., Le, Amy, Kachlany, Scott C., Connell, Nancy D., Kaplan, Jeffrey B.
Format: Artigo
Language:Inglês
Published: 2008
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Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC2586082/
https://ncbi.nlm.nih.gov/pubmed/18573331
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.micpath.2008.05.007
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