Aire controls the differentiation program of thymic epithelial cells in the medulla for the establishment of self-tolerance

The roles of autoimmune regulator (Aire) in the expression of the diverse arrays of tissue-restricted antigen (TRA) genes from thymic epithelial cells in the medulla (medullary thymic epithelial cells [mTECs]) and in organization of the thymic microenvironment are enigmatic. We approached this issue...

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Autors principals: Yano, Masashi, Kuroda, Noriyuki, Han, Hongwei, Meguro-Horike, Makiko, Nishikawa, Yumiko, Kiyonari, Hiroshi, Maemura, Kentaro, Yanagawa, Yuchio, Obata, Kunihiko, Takahashi, Satoru, Ikawa, Tomokatsu, Satoh, Rumi, Kawamoto, Hiroshi, Mouri, Yasuhiro, Matsumoto, Mitsuru
Format: Artigo
Idioma:Inglês
Publicat: The Rockefeller University Press 2008
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Articles
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC2585853/
https://ncbi.nlm.nih.gov/pubmed/19015306
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1084/jem.20080046
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