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Spt2p Defines a New Transcription-Dependent Gross Chromosomal Rearrangement Pathway
Large numbers of gross chromosomal rearrangements (GCRs) are frequently observed in many cancers. High mobility group 1 (HMG1) protein is a non-histone DNA-binding protein and is highly expressed in different types of tumors. The high expression of HMG1 could alter DNA structure resulting in GCRs. S...
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| Main Authors: | , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado: |
Public Library of Science
2008
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| Assuntos: | |
| Acceso en liña: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2585797/ https://ncbi.nlm.nih.gov/pubmed/19057669 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pgen.1000290 |
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