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Mimicking Stem Cell Niches to Increase Stem Cell Expansion

Niches regulate lineage-specific stem cell self-renewal vs. differentiation in vivo and are comprised of supportive cells and extracellular matrix components arranged in a 3-dimensional topography of controlled stiffness in the presence of oxygen and growth factor gradients. Mimicking stem cell nich...

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Autors principals: Dellatore, Shara M., Garcia, A. Sofia, Miller, William M.
Format: Artigo
Idioma:Inglês
Publicat: 2008
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC2585613/
https://ncbi.nlm.nih.gov/pubmed/18725291
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.copbio.2008.07.010
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