Prediction of TF target sites based on atomistic models of protein-DNA complexes

BACKGROUND: The specific recognition of genomic cis-regulatory elements by transcription factors (TFs) plays an essential role in the regulation of coordinated gene expression. Studying the mechanisms determining binding specificity in protein-DNA interactions is thus an important goal. Most current...

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Main Authors: Angarica, Vladimir Espinosa, Pérez, Abel González, Vasconcelos, Ana T, Collado-Vides, Julio, Contreras-Moreira, Bruno
Formato: Artigo
Idioma:Inglês
Publicado: BioMed Central 2008
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Research Article
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC2585596/
https://ncbi.nlm.nih.gov/pubmed/18922190
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1471-2105-9-436
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