Clinicopathological significance of expression of p-c-Jun, TCF4 and beta-Catenin in colorectal tumors

BACKGROUND: A recent study has shown that phosphorylated c-Jun (p-c-Jun) interacts with TCF4 to form a complex that cooperatively enhances their transcriptional activity in the presence of β-Catenin, and that their interaction is critical for mouse intestinal tumorigenesis. To determine the signific...

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Main Authors: Takeda, Kayoko, Kinoshita, Ichiro, Shimizu, Yasushi, Ohba, Yusuke, Itoh, Tomoo, Matsuno, Yoshihiro, Shichinohe, Toshiaki, Dosaka-Akita, Hirotoshi
Format: Artigo
Jezik:Inglês
Izdano: BioMed Central 2008
Teme:
Research Article
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC2585585/
https://ncbi.nlm.nih.gov/pubmed/18992165
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1471-2407-8-328
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