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DOPAMINE TRANSPORTER ENDOCYTIC DETERMINANTS: CARBOXY TERMINAL RESIDUES CRITICAL FOR BASAL AND PKC-STIMULATED INTERNALIZATION
Dopamine (DA) reuptake terminates dopaminergic neurotransmission and is mediated by DA transporters (DATs). Acute protein kinase C (PKC) activation accelerates DAT internalization rates, thereby reducing DAT surface expression. Basal DAT endocytosis and PKC-stimulated DAT functional downregulation r...
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| Main Authors: | , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2008
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2585501/ https://ncbi.nlm.nih.gov/pubmed/18638559 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.mcn.2008.06.011 |
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