GPRC6A Null Mice Exhibit Osteopenia, Feminization and Metabolic Syndrome

BACKGROUND: GPRC6A is a widely expressed orphan G-protein coupled receptor that senses extracellular amino acids, osteocalcin and divalent cations in vitro. The physiological functions of GPRC6A are unknown. METHODS/PRINCIPAL FINDINGS: In this study, we created and characterized the phenotype of GPR...

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Autors principals: Pi, Min, Chen, Ling, Huang, Min-Zhao, Zhu, Wenyu, Ringhofer, Brian, Luo, Junming, Christenson, Lane, Li, Benyi, Zhang, Jianghong, Jackson, P. David, Faber, Pieter, Brunden, Kurt R., Harrington, John J., Quarles, L. Darryl
Format: Artigo
Idioma:Inglês
Publicat: Public Library of Science 2008
Matèries:
Research Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC2585477/
https://ncbi.nlm.nih.gov/pubmed/19050760
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0003858
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