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Gating motions underlie AMPA receptor secretion from the endoplasmic reticulum

Ion channel biogenesis involves an intricate interplay between subunit folding and assembly. Channel stoichiometries vary and give rise to diverse functions, which impacts on neuronal signalling. AMPA glutamate receptor (AMPAR) assembly is modulated by RNA processing. Here, we provide mechanistic in...

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Autors principals: Penn, Andrew C, Williams, Stephen R, Greger, Ingo H
Format: Artigo
Idioma:Inglês
Publicat: Nature Publishing Group 2008
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC2585171/
https://ncbi.nlm.nih.gov/pubmed/18923416
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/emboj.2008.222
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