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Prosecutor: parameter-free inference of gene function for prokaryotes using DNA microarray data, genomic context and multiple gene annotation sources

BACKGROUND: Despite a plethora of functional genomic efforts, the function of many genes in sequenced genomes remains unknown. The increasing amount of microarray data for many species allows employing the guilt-by-association principle to predict function on a large scale: genes exhibiting similar...

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Main Authors: Blom, Evert Jan, Breitling, Rainer, Hofstede, Klaas Jan, Roerdink, Jos BTM, van Hijum, Sacha AFT, Kuipers, Oscar P
Format: Artigo
Jezik:Inglês
Izdano: BioMed Central 2008
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC2585105/
https://ncbi.nlm.nih.gov/pubmed/18939968
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1471-2164-9-495
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