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Evolutionary and functional divergence between the cystic fibrosis transmembrane conductance regulator and related ATP-binding cassette transporters

The cystic fibrosis transmembrane conductance regulator (CFTR) is a member of the ATP-binding cassette (ABC) transporter superfamily, an ancient family of proteins found in all phyla. In nearly all cases, ABC proteins are transporters that couple the hydrolysis of ATP to the transmembrane movement o...

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Autors principals: King Jordan, I., Kota, Karthik C., Cui, Guiying, Thompson, Christopher H., McCarty, Nael A.
Format: Artigo
Idioma:Inglês
Publicat: National Academy of Sciences 2008
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC2585040/
https://ncbi.nlm.nih.gov/pubmed/19020075
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0806306105
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