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Autoimmunity and oxidatively modified autoantigens

Oxidative damage mediated by reactive oxygen species results in the generation of deleterious by-products. The oxidation process itself and the proteins modified by these molecules are important mediators of cell toxicity and disease pathogenesis. Aldehydic products, mainly the 4-hydroxy-2-alkenals,...

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Bibliographic Details
Main Authors: Kurien, Biji T., Scofield, R. Hal
Format: Artigo
Language:Inglês
Published: 2008
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC2585037/
https://ncbi.nlm.nih.gov/pubmed/18625446
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.autrev.2008.04.019
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