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The T1799A point mutation is present in posterior uveal melanoma

An activating mutation in exon 15 of the BRAF gene is present in a high proportion of cutaneous pigmented lesions. Until recently this mutation had however only been identified in one case of posterior uveal melanoma. Despite this apparent lack of the BRAF mutation, inappropriate downstream activati...

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Bibliografiska uppgifter
Huvudupphovsmän: Janssen, C S, Sibbett, R, Henriquez, F L, McKay, I C, Kemp, E G, Roberts, F
Materialtyp: Artigo
Språk:Inglês
Publicerad: Nature Publishing Group 2008
Ämnen:
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC2584949/
https://ncbi.nlm.nih.gov/pubmed/18985043
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.bjc.6604731
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