Benzylidene derivatives of andrographolide inhibit growth of breast and colon cancer cells in vitro by inducing G(1) arrest and apoptosis

BACKGROUND AND PURPOSE: Andrographolide, the major phytoconstituent of Andrographis paniculata, was previously shown by us to have activity against breast cancer. This led to synthesis of new andrographolide analogues to find compounds with better activity than the parent compound. Selected benzylid...

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Hlavní autoři: Jada, S R, Matthews, C, Saad, M S, Hamzah, A S, Lajis, N H, Stevens, M F G, Stanslas, J
Médium: Artigo
Jazyk:Inglês
Vydáno: Nature Publishing Group 2008
Témata:
Research Papers
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC2584933/
https://ncbi.nlm.nih.gov/pubmed/18806812
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/bjp.2008.368
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