Inhibitory effect of salvinorin A, from Salvia divinorum, on ileitis-induced hypermotility: cross-talk between κ-opioid and cannabinoid CB(1) receptors

BACKGROUND AND PURPOSE: Salvinorin A, the active component of the hallucinogenic herb Salvia divinorum, inhibits intestinal motility through activation of κ-opioid receptors (KORs). However, this compound may have target(s) other than the KORs in the inflamed gut. Because intestinal inflammation upr...

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Detalhes bibliográficos
Main Authors: Capasso, R, Borrelli, F, Cascio, M G, Aviello, G, Huben, K, Zjawiony, J K, Marini, P, Romano, B, Di Marzo, V, Capasso, F, Izzo, A A
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2008
Assuntos:
Research Papers
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2584932/
https://ncbi.nlm.nih.gov/pubmed/18622408
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/bjp.2008.294
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