Coenzyme Q(10) supplementation rescues renal disease in Pdss2(kd/kd) mice with mutations in prenyl diphosphate synthase subunit 2

Homozygous mice carrying kd (kidney disease) mutations in the gene encoding prenyl diphosphate synthase subunit 2 (Pdss2(kd/kd)) develop interstitial nephritis and eventually die from end-stage renal disease. The PDSS2 polypeptide in concert with PDSS1 synthesizes the polyisoprenyl tail of coenzyme...

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Detaylı Bibliyografya
Asıl Yazarlar: Saiki, Ryoichi, Lunceford, Adam L., Shi, Yuchen, Marbois, Beth, King, Rhonda, Pachuski, Justin, Kawamukai, Makoto, Gasser, David L., Clarke, Catherine F.
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: American Physiological Society 2008
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Articles
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC2584909/
https://ncbi.nlm.nih.gov/pubmed/18784258
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajprenal.90445.2008
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