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Intact renal afferent arteriolar autoregulatory responsiveness in db/db mice

The db/db mouse is a genetic model of type 2 diabetes that exhibits progressive renal disease. Obesity, hyperglycemia, and albuminuria (822 ± 365 vs. 28 ± 8 μg/day) are evident in 18-wk-old db/db compared with db/m (lean littermate control) mice. Our goal was to determine the blood pressure (BP) phe...

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Detalhes bibliográficos
Main Authors: Park, Sungmi, Bivona, Benjamin J., Feng, Yumei, Lazartigues, Eric, Harrison-Bernard, Lisa M.
Formato: Artigo
Idioma:Inglês
Publicado em: American Physiological Society 2008
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2584903/
https://ncbi.nlm.nih.gov/pubmed/18753291
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajprenal.90417.2008
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