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Selective Inactivation of Socs3 in SF1 Neurons Improves Glucose Homeostasis without Affecting Body Weight

Suppressor of cytokine signaling 3 (Socs3) has been identified as a mediator of central leptin resistance, but the identity of specific neurons in which Socs3 acts to suppress leptin signaling remains elusive. The ventromedial hypothalamus (VMH) was recently shown to be an important site for leptin...

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Detalhes bibliográficos
Main Authors: Zhang, Ren, Dhillon, Harveen, Yin, Huali, Yoshimura, Akihiko, Lowell, Bradford B., Maratos-Flier, Eleftheria, Flier, Jeffrey S.
Formato: Artigo
Idioma:Inglês
Publicado em: The Endocrine Society 2008
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2584592/
https://ncbi.nlm.nih.gov/pubmed/18669597
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1210/en.2008-0805
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