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Classical Estrogen Receptor α Signaling Mediates Negative and Positive Feedback on Gonadotropin-Releasing Hormone Neuron Firing
During the female reproductive cycle, the neuroendocrine action of estradiol switches from negative feedback to positive feedback to initiate the preovulatory GnRH and subsequent LH surges. Estrogen receptor-α (ERα) is required for both estradiol negative and positive feedback regulation of LH. ERα...
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| Main Authors: | , , , |
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| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
The Endocrine Society
2008
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2584581/ https://ncbi.nlm.nih.gov/pubmed/18635656 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1210/en.2008-0520 |
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