Immunization against anthrax with aromatic compound-dependent (Aro-) mutants of Bacillus anthracis and with recombinant strains of Bacillus subtilis that produce anthrax protective antigen.

The safety and efficacy of five prototype, live anthrax vaccines were studied in Hartley guinea pigs and CBA/J and A/J mice. Two of the strains, Bacillus anthracis FD111 and FD112, are Aro- mutants derived by Tn916 mutagenesis of B. anthracis UM23-1. Bacillus subtilis PA1 and PA2 contain a recombina...

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Bibliografski detalji
Izdano u:Infect Immun
Glavni autori: Ivins, B E, Welkos, S L, Knudson, G B, Little, S F
Format: Artigo
Jezik:Inglês
Izdano: American Society for Microbiology (ASM) 1990
Teme:
Research Article
Online pristup:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC258455/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/2105269/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/iai.58.2.303-308.1990
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