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Role of secondary structure in protein-phospholipid surface interactions: Reconstitution and denaturation of apoC-I:DMPC complexes

Protein binding to phospholipid surface is commonly mediated by amphipathic α-helices. To understand the role of α-helical structure in protein-lipid interactions, we used discoidal lipoproteins reconstituted from dimyristoyl phosphatidylcholine (DMPC) and human apolipoprotein C-I (apoC-I, 6 kD) or...

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Autori principali: Benjwal, Sangeeta, Jayaraman, Shobini, Gursky, Olga
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2007
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC2584444/
https://ncbi.nlm.nih.gov/pubmed/17341095
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/bi062175c
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