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Human activated protein C variants in a rat model of arterial thrombosis
BACKGROUND: Activated protein C (APC) inhibits coagulation by degrading activated factor V (FVa) and factor VIII (FVIIIa), protein S (PS) functioning as a cofactor to APC. METHODS: By mutagenesis of the vitamin K-dependent Gla domain of APC, we have recently created an APC variant having enhanced an...
Gorde:
| Egile Nagusiak: | , , |
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| Formatua: | Artigo |
| Hizkuntza: | Inglês |
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BioMed Central
2008
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| Gaiak: | |
| Sarrera elektronikoa: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2584025/ https://ncbi.nlm.nih.gov/pubmed/18957140 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1477-9560-6-16 |
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