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Age-Dependent Evolution of the Yeast Protein Interaction Network Suggests a Limited Role of Gene Duplication and Divergence

Proteins interact in complex protein–protein interaction (PPI) networks whose topological properties—such as scale-free topology, hierarchical modularity, and dissortativity—have suggested models of network evolution. Currently preferred models invoke preferential attachment or gene duplication and...

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Autors principals: Kim, Wan Kyu, Marcotte, Edward M.
Format: Artigo
Idioma:Inglês
Publicat: Public Library of Science 2008
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC2583957/
https://ncbi.nlm.nih.gov/pubmed/19043579
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pcbi.1000232
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