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Increased 5-Lipoxygenase Immunoreactivity in the Hippocampus of Patients With Alzheimer's Disease

The proinflammatory enzyme 5-lipoxygenase (5-LOX) is upregulated in Alzheimer's disease (AD), but its localization and association with the hallmark lesions of the disease, β-amyloid (Aβ) plaques and neurofibrillary tangles (NFTs), is unknown. This study examined the distribution and cellular l...

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Detalhes bibliográficos
Main Authors: Ikonomovic, Milos D., Abrahamson, Eric E., Uz, Tolga, Manev, Hari, DeKosky, Steven T.
Formato: Artigo
Idioma:Inglês
Publicado em: Histochemical Society 2008
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2583907/
https://ncbi.nlm.nih.gov/pubmed/18678882
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1369/jhc.2008.951855
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