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Kaposi's Sarcoma-Associated Herpesvirus Disrupts Adherens Junctions and Increases Endothelial Permeability by Inducing Degradation of VE-Cadherin

Kaposi's sarcoma (KS) is a vascular tumor of proliferative endothelial cells caused by KS-associated herpesvirus (KSHV) infection. Aberrant vascular permeability is a hallmark of KS manifested as multifocal edematous skin and visceral lesions with dysregulated angiogenesis and vast inflammatory...

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Detalhes bibliográficos
Main Authors: Qian, Li-Wu, Greene, Whitney, Ye, Fengchun, Gao, Shou-Jiang
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology (ASM) 2008
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2583667/
https://ncbi.nlm.nih.gov/pubmed/18815301
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.01042-08
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