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Induction of Cellular Stress Overcomes the Requirement of Herpes Simplex Virus Type 1 for Immediate-Early Protein ICP0 and Reactivates Expression from Quiescent Viral Genomes

Herpes simplex virus type 1 (HSV-1) mutants impaired in the activities of the structural protein VP16 and the immediate-early (IE) proteins ICP0 and ICP4 establish a quiescent infection in human fibroblasts, with most cells retaining an inactive, repressed viral genome for sustained periods in cultu...

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Bibliografske podrobnosti
Main Authors: Preston, Chris M., Nicholl, Mary Jane
Format: Artigo
Jezik:Inglês
Izdano: American Society for Microbiology (ASM) 2008
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC2583663/
https://ncbi.nlm.nih.gov/pubmed/18799580
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.01273-08
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