Modification of Lipooligosaccharide with Phosphoethanolamine by LptA in Neisseria meningitidis Enhances Meningococcal Adhesion to Human Endothelial and Epithelial Cells

The lipooligosaccharide (LOS) of Neisseria meningitidis can be decorated with phosphoethanolamine (PEA) at the 4′ position of lipid A and at the O-3 and O-6 positions of the inner core of the heptose II residue. The biological role of PEA modification in N. meningitidis remains unclear. During the c...

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Main Authors: Takahashi, Hideyuki, Carlson, Russel W., Muszynski, Artur, Choudhury, Biswa, Kim, Kwang Sik, Stephens, David S., Watanabe, Haruo
Formato: Artigo
Idioma:Inglês
Publicado: American Society for Microbiology (ASM) 2008
Assuntos:
Cellular Microbiology: Pathogen-Host Cell Molecular Interactions
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC2583577/
https://ncbi.nlm.nih.gov/pubmed/18824535
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/IAI.00676-08
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